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Neurological Sciences,
THE CANADIAN JOURNAL OF
LE JOURNAL CANADIEN
DES
Sciences Neurologiques
Tissue
Plasminogen Activator in a Vertebral Artery Dissection
Andrew P. Gasecki, Carmelo
Graffagnino and Vladimir Hachinski
Abstract: Background: Spontaneous dissection of the vertebral
artery is uncommon. Method: Case study. Results: We
report a 49-year-old woman who presented with the rapidly progressing basilar
artery syndrome who was given an intravenous dose of tissue plasminogen
activator seven hours after the onset of first symptoms. Thirty minutes after
the injection, a dramatic recovery of the patient's consciousness and
neurological signs was noted. Conclusion: To our knowledge, this
is the first reported case of intravenous tissue plasminogen activator use in
acute vertebral artery dissection.
Can. J. Neurol. Sci. 1997; 24: 151-154
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