Dear Doctors and health professionals:

We all recognize the immune modulation, and cancer inhibition property of Coriolus, and I wish to clarify a very important point that you as health professionals should be aware of.

Mycelium of mushroom, similar to the stage of bean sprouts, or alfalfa sprout, is the most nutritious stage of the mushroom, which is tender and soft. Mycelium is not like fruiting body (the mushroom we usually see is called fruiting body) which are encapsulated and protected by indigestible hard woody fibrous cell walls, which prevent conventional methods from extracting the nutrients, and human digestion. 

PSP is a large complex, molecular weight at 1 x 10⁵ Da. formed by many monosaccharides that are structurally bonded together with proteins (peptide) located intracellularly, i.e., inside and on the cell walls. One must break the cell walls of the mycelium to extract PSP complex. Conventional hot water extraction of polysaccharide claimed on some products is not  as  effective as true Polysaccharide Peptide compound. 

The keys for selection of a correct product are:

1. The type of mushroom. "Coriolus versicolor" (Cloud mushroom, Yun-zhi, Turkey tail).

2. The strain of mushroom. CM-101 makes PSK, Cov-1 makes PSP.

3. The source and method of extraction. "100% Mycelium & Intracellular Extract. (Sterilized media, absolutely no heavy metal, yeast or pathogens)

4. Intracellular extract from mycelium requires the same technology as making antibodies, which requires a group of highly refined technologies working together.  Don't be confused with fruiting body extract, non-intercellular substitute products being offered to the public.  

5. PSP is more than just simple Coriolus mushroom extract.

6. Naturally extracted  ranging from 18%- 65% of  Polysaccharide peptide complex, so as to take the advantages of all fractions of the Coriolus, and  not lose other nutrients in the formulation, higher concentration is possible but is not needed..

7. Wild fruiting body is seasonal, and it's difficult to control their freshness, quality, and the environment where they were collected from, all of which contribute to unaffordable high price. ( Organic ?? )

8. PSP contains more then only Alpha 1,4;  beta 1,3  and beta 1,6 glucans.  Its different types of non-digestible  monosaccharides act as "cheating" agents to starve the cancer cells, also to stimulates the immune system.  Its peptide act to create more open address for lymphocytes thus enhances the  immune function. 

9. PSP is a very effective delivery vehicle, its polysaccharides and peptide offer many open address to the receptors thus could be used to carry many substance to their desired  location. It opens  channels and meridians;  it enhances other substances.  It is highly advantageous to use PSP within other formulas.

10. Check on the Blood pictures, increasing of WBC,  increasing in lymphocyte ( NK cells),  and reduction of Eosinophile, and basophile. 

Sincerely Yours,

PSP Extracts Inc.

Other mushroom mycelium extracts such as Cordyceps sinensis, Ganoderma lucidum (Reishi), Polyporus frondosus (Maetake), Lentinus edodes(Shiitake) are available upon request.

Table IV. The inhibitory effect of  SPCV, PSP, and PSK on leukemia cell

• HL-60 cells were cultured with different concentration of drugs

• for 48 hrs. Cytotoxic activities of the drugs were assessed by ³ H-TdR incorporation for 24 hrs.

• *Data obtained from the report of Shanghai Teachers University (17).