Aspirin (Salicylic acid)
Aspirin could be used for reducing the risk of recurrent transient ischemic attacks (TIA's) or
stroke in men who have had transient ischemia of the brain due to fibrin
platelet emboli. There is inadequate evidence that aspirin is
effective in reducing TIA's in women at the recommended dosage. There is no evidence
that aspirin is of benefit in the treatment of completed strokes in men or
women.
Source: The Canadian Cooperative Study Group. New England Journal of
Medicine, 299:53-59, 1978.
Aspirin should be used with caution when anticoagulants are prescribed
concurrently, for aspirin may depress the concentration of prothrombin in plasma
and thereby increase bleeding time. Large dose of salicylates have a
hypoglycemic action and may enhance the effect of the oral hypoglycemics. |