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Aspirin (Salicylic acid)

Aspirin could be used for reducing the risk of recurrent transient ischemic attacks (TIA's) or stroke in men who have had transient ischemia of the brain due to fibrin platelet emboli.  There is inadequate evidence that aspirin  is effective in reducing TIA's in women at the recommended dosage. There is no evidence that aspirin is of benefit in the treatment of completed strokes in men or women. 

Source: The Canadian Cooperative Study Group. New England Journal of Medicine, 299:53-59, 1978.

 

Aspirin should be used with caution when anticoagulants are prescribed concurrently, for aspirin may depress the concentration of prothrombin in plasma and thereby increase bleeding time.  Large dose of salicylates have a hypoglycemic action and may enhance the effect of the oral hypoglycemics.